Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD11660 ...
Drug Name Latanoprostene bunod
Molecular Weight 507.624
Molecular Formula C27H41NO8
CAS Number 860005-21-6
SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(=O)OCCCCO[N+]([O-])=O)CCC1=CC=CC=C1
External Links
DRUGBANK DB11660
PubChem Compound 11156438
PDR 24155

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
C Max 0.0591 ng/ml 59.1 pg/ml normal,healthy; Derivative; DRUGBANK
T Max 0.0833 h 5 min normal,healthy; Derivative; DRUGBANK
Half-life 1.8 h 1.8 h rabbit; DRUGBANK
Half-life 2.1 h 2.1 h rabbit; DRUGBANK
Half-life 4.6 h 4.6 h rabbit; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for neonates 0.0 0 Vyzulta latanoprostene bunod PDR
Max dose for infants 0.0 0 Vyzulta latanoprostene bunod PDR
Max dose for children 0.0 0 Vyzulta latanoprostene bunod PDR
Max dose for adolescents 1.0 drop/day 1 drop/day ophthalmic administration Vyzulta latanoprostene bunod PDR
Max dose for adolescents 0.0 0 Vyzulta latanoprostene bunod PDR
Max dose for adults 1.0 drop/day 1 drop/day ophthalmic administration Vyzulta latanoprostene bunod PDR
Max dose for geriatric 1.0 drop/day 1 drop/day ophthalmic administration Vyzulta latanoprostene bunod PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1