Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.62 | - | 3.62 | - | https://www.chemsrc.com/en/cas/937263-43-9_731232.html |
| Melting Point | 230.0 | ℃ | 230 | ℃ | https://sss.hovione.com/SDSSearch/SSS.aspx?Id=1893 |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| AUC | 7120.0 | ng.h/ml | 7120.0 | ng.h/ml | different study; | DRUGBANK |
| C Max | 1120.0 | ng/ml | 1120 | ng/ml | different study; | DRUGBANK |
| T Max | 2.5 | h | 1-4 | h | DRUGBANK | T Max | 2.0 | h | 1-3 | h | different study; | DRUGBANK |
| Clearance | 148.0 | L/h | 148.0 | L/h | apparent clearance; | DRUGBANK |
| Volume of Distribution | 1670.0 | L | 1670.0 | L | DRUGBANK | |
| Half-life | 5.4 | h | ~5.38 | h | DRUGBANK | Half-life | 8.2 | h | ~8.21 | h | elimination half-life; | DRUGBANK |
| Eliminate Route | 86.0 | % | ~86 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 4.1 | % | ~4.1 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 13.8 | % | 13.76 | % | Faeces excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 97.0 | % | ~97 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1