Basic Information
| Drug ID | DDPD11641 |
|
| Drug Name | Vinflunine | |
| Molecular Weight | 816.944 | |
| Molecular Formula | C45H54F2N4O8 | |
| CAS Number | 162652-95-1 | |
| SMILES | CC[C@@]12C=CCN3CC[C@@]4([C@H]13)[C@@H](N(C)C1=CC(OC)=C(C=C41)[C@]1(C[C@@H]3C[C@H](C[N@@](C3)CC3=C1NC1=CC=CC=C31)C(C)(F)F)C(=O)OC)[C@](O)([C@@H]2OC(C)=O)C(=O)OC | |
| External Links | ||
| DRUGBANK | DB11641 | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 244.0 | ℃ | 244 | ℃ | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 40.0 | L/h | 40.0 | L/h | Total clearance; | DRUGBANK |
| Volume of Distribution | 2422.0 | L | 2422±676 | L | DRUGBANK | |
| Half-life | 40.0 | h | ~40 | h | terminal half-life; | DRUGBANK | Half-life | 120.0 | h | ~120 | h | Metabolite; | DRUGBANK |
| Eliminate Route | 66.7 | % | ~66.7 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 33.3 | % | ~33.3 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 67.2 | % | 67.2±1.1 | % | plasma proteins; human, homo sapiens; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1