Basic Information
| Drug ID | DDPD11630 |
|
| Drug Name | Temoporfin | |
| Molecular Weight | 680.764 | |
| Molecular Formula | C44H32N4O4 | |
| CAS Number | 122341-38-2 | |
| SMILES | OC1=CC=CC(=C1)C-1=C2\CCC(=N2)\C(=C2/N\C(\C=C2)=C(/C2=N/C(/C=C2)=C(\C2=CC=C\-1N2)C1=CC(O)=CC=C1)C1=CC(O)=CC=C1)\C1=CC(O)=CC=C1 | |
| External Links | ||
| DRUGBANK | DB11630 | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 3.0 | h | 2-4 | h | intravenous injection, IV; | DRUGBANK |
| Clearance | 0.004000 | L/h/kg | 3.9-4.1 | ml/h/kg | DRUGBANK | Clearance | 0.003600 | L/h/kg | 0.06 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.40 | L/kg | 0.34-0.46 | L/kg | DRUGBANK | |
| Half-life | 65.0 | h | 65 | h | terminal half-life; | DRUGBANK | Half-life | 30.0 | h | 30 | h | distribution half-life; | DRUGBANK | Half-life | 68.0 | h | 68 | h | terminal half-life; | DRUGBANK | Half-life | 91.5 | h | 91.5 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 86.5 | % | 85-88 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1