Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD11614 ...
Drug Name Rupatadine
Molecular Weight 415.97
Molecular Formula C26H26ClN3
CAS Number 158876-82-5
SMILES CC1=CC(CN2CCC(CC2)=C2C3=CC=C(Cl)C=C3CCC3=C2N=CC=C3)=CN=C1
External Links
DRUGBANK DB11614
PubChem Compound 133017

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 0.8 - 0.8 - FDA Label
Melting Point 197.5 ℃ 194-201 ℃ FDA Label

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Factor Reference
T Max 1.0 h 1 h DRUGBANK
T Max 2.0 h 2 h high-fat meal; high-fat meal ↑ ; DRUGBANK
Clearance 1556.2 L/h 1556.2 L/h Total clearance; young; adults; DRUGBANK
Clearance 798.2 L/h 798.2 L/h Total clearance; Geriatric; DRUGBANK
Volume of Distribution 9799.0 L 9799.0 L Apparent volume of distribution; DRUGBANK
Half-life 15.9 h 15.9 h Children; DRUGBANK
Half-life 12.3 h 12.3 h Children; DRUGBANK
Half-life 5.9 h 5.9 h adults; DRUGBANK
Half-life 8.7 h 8.7 h Geriatric; DRUGBANK
Protein Binding 98.8 % 98.5-99.0 % plasma proteins; human, homo sapiens; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1