Basic Information
| Drug ID | DDPD11613 |
|
| Drug Name | Velpatasvir | |
| Molecular Weight | 883.019 | |
| Molecular Formula | C49H54N8O8 | |
| CAS Number | 1377049-84-7 | |
| SMILES | COC[C@H]1C[C@H](N(C1)C(=O)[C@H](NC(=O)OC)C1=CC=CC=C1)C1=NC=C(N1)C1=CC=C2C(COC3=CC4=C(C=CC5=C4NC(=N5)[C@@H]4CC[C@H](C)N4C(=O)[C@@H](NC(=O)OC)C(C)C)C=C23)=C1 | |
| External Links | ||
| DRUGBANK | DB11613 | |
| PubChem Compound | 67683363 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 27.5 | % | 25-30 | % | DRUGBANK | |
| Clearance | 0.12 | L/h/kg | 0.12 | L/h/kg | DRUGBANK | |
| Volume of Distribution | 1.5 | L/kg | 1.4-1.6 | L/kg | DRUGBANK | |
| Half-life | 15.0 | h | 15 | h | DRUGBANK | |
| Eliminate Route | 94.0 | % | 94 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 0.40 | % | 0.4 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 99.5 | % | >99.5 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1