Basic Information
| Drug ID | DDPD11575 |
|
| Drug Name | Grazoprevir | |
| Molecular Weight | 766.903 | |
| Molecular Formula | C38H50N6O9S | |
| CAS Number | 1350514-68-9 | |
| SMILES | COC1=CC2=NC3=C(CCCCC[C@@H]4C[C@H]4OC(=O)N[C@H](C(=O)N4C[C@@H](C[C@H]4C(=O)N[C@@]4(C[C@H]4C=C)C(=O)NS(=O)(=O)C4CC4)O3)C(C)(C)C)N=C2C=C1 | |
| External Links | ||
| DRUGBANK | DB11575 | |
| PubChem Compound | 44603531 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 27.0 | % | 27 | % | DRUGBANK | |
| T Max | 2.0 | h | 0.5-3.5 | h | DRUGBANK | |
| Volume of Distribution | 1250.0 | L | 1250.0 | L | Apparent volume of distribution; | DRUGBANK |
| Half-life | 31.0 | h | 31 | h | terminal half-life; HCV-positive; | DRUGBANK |
| Eliminate Route | 90.0 | % | 90 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 1.0 | % | <1 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 98.8 | % | >98.8 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1