Basic Information
| Drug ID | DDPD11560 |
|
| Drug Name | Lesinurad | |
| Molecular Weight | 404.28 | |
| Molecular Formula | C17H14BrN3O2S | |
| CAS Number | 878672-00-5 | |
| SMILES | OC(=O)CSC1=NN=C(Br)N1C1=CC=C(C2CC2)C2=C1C=CC=C2 | |
| External Links | ||
| DRUGBANK | DB11560 | |
| PubChem Compound | 53465279 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 2.5 | h | 1-4 | h | PO, oral; food; fasting; | DRUGBANK |
| Clearance | 0.0858 | L/h/kg | 1.43 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 20.0 | L | 20.0 | L | Steady state volume of distribution; intravenous injection, IV; | DRUGBANK | Volume of Distribution | 0.29 | L/kg | 0.29 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 5.0 | h | 5 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route | 63.0 | % | 63 | % | Urinary excretion; Oral single dose; | DRUGBANK | Eliminate Route | 32.0 | % | 32 | % | Faeces excretion; Oral single dose; | DRUGBANK | Eliminate Route | 30.0 | % | ~30 | % | Urinary excretion; Oral single dose; Unchanged drug; | DRUGBANK |
| Protein Binding | 98.0 | % | >98 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1