Basic Information
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Factor | Reference |
|---|---|---|---|---|---|---|---|
| C Max | 909000.0 | ng/ml | 909±165 | mg/L | intravenous infusion, IV in drop; | increasing doses ↑ ; | DRUGBANK |
| Css | 522000.0 | ng/ml | 522±118 | mg/L | intravenous infusion, IV in drop; | increasing doses ↑ ; | DRUGBANK |
| Clearance | 4.4 | L/h | 4.40±0.77 | L/h | Average clearance; intravenous infusion, IV in drop; normal,healthy; | DRUGBANK | |
| Clearance | 5.2 | L/h | 5.21±1.28 | L/h | Renal clearance; | DRUGBANK | |
| Volume of Distribution | 0.002130 | L/kg | 2.13 | ml/kg | Steady state volume of distribution; intravenous infusion, IV in drop; Rattus, Rat; normal,healthy; Preg, pregnant; | DRUGBANK | |
| Volume of Distribution | 30.0 | mg/kg/h | 720.0 | mg/kg/day | Steady state volume of distribution; dog; | DRUGBANK | |
| Half-life | 18.0 | h | 18 | h | human, homo sapiens; | DRUGBANK | |
| Half-life | 7.7 | h | ~7.65±1.10 | h | elimination half-life; normal,healthy; intravenous infusion, IV in drop; | DRUGBANK | |
| Toxicity LD50 | 9380.0 | mg/kg | 9380.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1