Basic Information
| Drug ID | DDPD11273 |
|
| Drug Name | Dihydroergocornine | |
| Molecular Weight | 563.699 | |
| Molecular Formula | C31H41N5O5 | |
| CAS Number | 25447-65-8 | |
| SMILES | [H][C@@]12CCCN1C(=O)[C@H](C(C)C)N1C(=O)[C@](NC(=O)[C@H]3CN(C)[C@]4([H])CC5=CNC6=CC=CC(=C56)[C@@]4([H])C3)(O[C@@]21O)C(C)C | |
| External Links | ||
| DRUGBANK | DB11273 | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.33 | - | 2.33 | - | ChemSrc |
| Melting Point | 187.0 | ℃ | 187 | ℃ | Florey K. Analytical profiles of drug substances. 1978. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 25.0 | % | 25 | % | PO, oral; | DRUGBANK |
| C Max | 0.57 | ngEq/ml | 0.57 | ngEq/ml | PO, oral; | DRUGBANK |
| T Max | 1.4 | h | 1.4 | h | PO, oral; | DRUGBANK |
| Half-life | 3.5 | h | 3.5 | h | elimination half-life; | DRUGBANK | Half-life | 13.0 | h | 13 | h | terminal half-life; | DRUGBANK |
| Eliminate Route | 100.0 | % | ~100 | % | Faeces excretion; PO, oral; | DRUGBANK | Eliminate Route | 2.5 | % | 2.5 | % | Urinary excretion; PO, oral; | DRUGBANK | Eliminate Route | 10.0 | % | 10 | % | Urinary excretion; intravenous injection, IV; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1