Basic Information

Drug ID DDPD11156 ...
Drug Name Pyrantel
Molecular Weight 206.31
Molecular Formula C11H14N2S
CAS Number 15686-83-6
SMILES [H]\C(=C(\[H])C1=NCCCN1C)C1=CC=CS1
External Links
DRUGBANK DB11156
PubChem Compound 708857
PDR 2158

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Absorption 0 % 0 % PO, oral; DRUGBANK
T Max 2.0 h 1-3 h DRUGBANK
Half-life 1.8 h 1.75±0.19 h intravenous injection, IV; pig; DRUGBANK
Toxicity LD50 535.0 mg/kg 535.0 mg/kg Rattus, Rat; DRUGBANK
Eliminate Route 7.0 % <7 % Urinary excretion; Unchanged drug; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for infants 11.0 mg/kg/dose 11 mg/kg/dose PO, oral Reese's Pinworm Medicine (pyrantel pamoate) PDR
Max dose for children 11.0 mg/kg/dose 11 mg/kg/dose PO, oral Reese's Pinworm Medicine (pyrantel pamoate) PDR
Max dose for children 11.0 mg/kg/dose 11 mg/kg/dose PO, oral Reese's Pinworm Medicine (pyrantel pamoate) PDR
Max dose for children 1000.0 mg/dose 1 g/dose PO, oral Reese's Pinworm Medicine (pyrantel pamoate) PDR
Max dose for adolescents 11.0 mg/kg/dose 11 mg/kg/dose PO, oral Reese's Pinworm Medicine (pyrantel pamoate) PDR
Max dose for adolescents 1000.0 mg/dose 1 g/dose PO, oral Reese's Pinworm Medicine (pyrantel pamoate) PDR
Max dose for adults 11.0 mg/kg/dose 11 mg/kg/dose PO, oral Reese's Pinworm Medicine (pyrantel pamoate) PDR
Max dose for adults 1000.0 mg/dose 1 g/dose PO, oral Reese's Pinworm Medicine (pyrantel pamoate) PDR
Max dose for geriatric 11.0 mg/kg/dose 11 mg/kg/dose PO, oral Reese's Pinworm Medicine (pyrantel pamoate) PDR
Max dose for geriatric 1.0 g/dose 1 g/dose PO, oral Reese's Pinworm Medicine (pyrantel pamoate) PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1