Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 194.0 | ℃ | 194 | ℃ | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 23.5 | % | 17-30 | % | PO, oral; | DRUGBANK | Absorption | 0.57 | % | 0.57 | % | PO, oral; rabbit; | DRUGBANK |
| Clearance | 0.008870 | L/h/kg | 8.87±1.76 | ml/h/kg | PO, oral; | DRUGBANK |
| Volume of Distribution | 0.0384 | L/kg | 38.4±6.4 | ml/kg | Steady state volume of distribution; PO, oral; | DRUGBANK |
| Half-life | 5.3 | h | 5.29±0.47 | h | PO, oral; | DRUGBANK |
| Toxicity LD50 | 3470.0 | mg/kg | 3470.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 2000.0 | mg/kg | >2 | g/kg | skin/dermal; rabbit; | DRUGBANK |
| Protein Binding | 98.0 | % | ~98 | % | plasma proteins; PO, oral; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1