Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD09512 ...
Drug Name Simethicone
Molecular Weight 238.461
Molecular Formula C6H18O4Si3
CAS Number 8050-81-5
SMILES O=[Si]=O.CO[Si](C)(C)O[Si](C)(C)C
External Links
DRUGBANK DB09512
PDR 2675

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Absorption 0 % 0 % PO, oral; DRUGBANK
Metabolic 100.0 % 100 % Faeces excretion; DRUGBANK
Toxicity LD50 4070.0 mg/kg 4070.0 mg/kg PO, oral; Rattus, Rat; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for infants 240.0 mg/day 240 mg/day PO, oral Gas-X simethicone PDR
Max dose for children 480.0 mg/day 480 mg/day PO, oral Gas-X simethicone PDR
Max dose for children 240.0 mg/day 240 mg/day PO, oral Gas-X simethicone PDR
Max dose for adolescents 480.0 mg/day 480 mg/day PO, oral Gas-X simethicone PDR
Max dose for adults 500.0 mg/day 500 mg/day PO, oral Gas-X simethicone PDR
Max dose for geriatric 500.0 mg/day 500 mg/day PO, oral Gas-X simethicone PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1