Basic Information
| Drug ID | DDPD09488 |
|
| Drug Name | Acrivastine | |
| Molecular Weight | 348.4382 | |
| Molecular Formula | C22H24N2O2 | |
| CAS Number | 87848-99-5 | |
| SMILES | [H]\C(CN1CCCC1)=C(\C1=CC=C(C)C=C1)C1=CC=CC(=N1)C(\[H])=C(/[H])C(O)=O | |
| External Links | ||
| DRUGBANK | DB09488 | |
| PubChem Compound | 5284514 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 1.1 | h | 1.14±0.23 | h | Capsule, PO, Oral; | DRUGBANK |
| Clearance | 0.17 | L/h/kg | 2.9±0.7 | ml/min/kg | DRUGBANK | |
| Volume of Distribution | 0.46 | L/kg | 0.46±0.05 | L/kg | DRUGBANK | |
| Half-life | 1.9 | h | 1.9±0.3 | h | terminal half-life; Oral single dose; | DRUGBANK |
| Half-life | 3.5 | h | 3.5±1.9 | h | terminal half-life; at steady state; | DRUGBANK |
| Half-life | 3.8 | h | 3.8±1.4 | h | Metabolite; | DRUGBANK |
| Eliminate Route | 84.0 | % | ~84 | % | Urinary excretion; normal,healthy; human, homo sapiens; | DRUGBANK |
| Eliminate Route | 13.0 | % | ~13 | % | Faeces excretion; normal,healthy; human, homo sapiens; | DRUGBANK |
| Protein Binding | 50.0 | % | 50±2 | % | plasma proteins; human, homo sapiens; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1