Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 245.0 | ℃ | 245 | ℃ | DRUGBANK |
| Water Solubility | 5000.0 | mg/L | 5 | mg/ml | Sigma-aldrich MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| AUC | 301.0 | ng.h/ml | 301.0 | ng.h/ml | Oral single dose; | DRUGBANK |
| C Max | 69.0 | ng/ml | 69 | ng/ml | Oral single dose; | DRUGBANK |
| T Max | 3.0 | h | 3 | h | Oral single dose; | DRUGBANK |
| Clearance | 109.0 | L/h | 109.0 | L/h | tumor; patients; | DRUGBANK |
| Volume of Distribution | 333.0 | L | 333.0 | L | Drug combination; tumor; patients; | DRUGBANK |
| Half-life | 2.1 | h | 2.1 | h | elimination half-life; | DRUGBANK |
| Eliminate Route | 49.7 | % | 49.7 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 27.0 | % | 27 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 21.4 | % | 21.357 | % | Urinary excretion; Unchanged drug; | DRUGBANK | Eliminate Route | 24.0 | % | 23.96 | % | Faeces excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 8.0 | % | <8 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1