Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD09327 ...
Drug Name Tegafur-uracil
Molecular Weight 312.257
Molecular Formula C12H13FN4O5
CAS Number 74578-38-4
SMILES O=C1NC=CC(=O)N1.FC1=CN(C2CCCO2)C(=O)NC1=O
External Links
DRUGBANK DB09327
PubChem Compound 104747

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Css 1000.0 ng/ml >1000 ng/ml DRUGBANK
T Max 1.5 h 1-2 h DRUGBANK
T Max 0.75 h 0.5-1 h Derivative; DRUGBANK
Clearance 6.7 L/h 47-175 ml/min DRUGBANK
Volume of Distribution 59.0 L 59.0 L DRUGBANK
Volume of Distribution 474.0 L 474.0 L DRUGBANK
Half-life 11.0 h 11 h DRUGBANK
Half-life 0.50 h 20-40 min elimination half-life; DRUGBANK
Protein Binding 52.0 % 52 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1