| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| Absorption |
90.0 |
% |
90 |
% |
PO, oral; |
DRUGBANK |
| AUC |
1140.0 |
ng.h/ml |
1.14±0.12 |
ug.h/ml |
PO, oral; different study; |
DRUGBANK |
| Bioavailability |
100.0 |
% |
~100 |
% |
PO, oral; fasting; |
DRUGBANK |
| C Max |
848.0 |
ng/ml |
848±116 |
ng/ml |
Liquid; |
DRUGBANK |
| T Max |
0.67 |
h |
0.33-1 |
h |
PO, oral; |
DRUGBANK |
T Max |
0.46 |
h |
0.46±0.17 |
h |
Liquid; |
DRUGBANK |
| Clearance |
4.6 |
L/h |
77.4±11.2 |
ml/min |
Renal clearance; Tablet, PO, oral; normal,healthy; young; adults; |
DRUGBANK |
Clearance |
4.7 |
L/h |
78.4 ± 6.9 |
ml/min |
Renal clearance; Tablet, PO, oral; normal,healthy; young; adults; |
DRUGBANK |
Clearance |
2.4 |
L/h |
35-45 |
ml/min |
Renal clearance; |
DRUGBANK |
| Half-life |
6.5 |
h |
3-10 |
h |
elimination half-life; |
DRUGBANK |
Half-life |
172800.0 |
h |
20 |
year |
|
DRUGBANK |
| Toxicity LD50 |
44.0 |
mg/kg |
44.0 |
mg/kg |
PO, oral; mouse; |
DRUGBANK |
Toxicity LD50 |
31.0 |
mg/kg |
31.0 |
mg/kg |
PO, oral; Rattus, Rat; |
DRUGBANK |
Toxicity LD50 |
200.0 |
mg/kg |
200.0 |
mg/kg |
PO, oral; rabbit; |
DRUGBANK |
| Toxicity MRLs |
0.0500 |
mg/kg/day |
0.05 |
mg/kg/day |
PO, oral; Oral multiple dose; |
ATSDR |
| Eliminate Route |
10.0 |
% |
~10 |
% |
Faeces excretion; |
DRUGBANK |
