Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 341.6 | ℃ | 339.8-343.4 | ℃ | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 1.5 | h | 1-2 | h | DRUGBANK | |
| Clearance | 0.0570 | L/h/kg | 0.95 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 16.0 | L/m2 | 16.0 | L/m2 | DRUGBANK | Volume of Distribution | 0.62 | L/kg | 0.62 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 11.0 | h | ~11 | h | elimination half-life; | DRUGBANK | Half-life | 8.7 | h | 8.69 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 930.0 | mg/kg | 930.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 775.0 | mg/kg | 775.0 | mg/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 340.0 | mg/kg | 340.0 | mg/kg | PO, oral; dog; | DRUGBANK |
| Eliminate Route | 20.0 | % | <20 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 52.3 | % | 52.3 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1