Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 201.0 | ℃ | 197-205 | ℃ | MSDS |
| Water Solubility | 1000.0 | mg/L | <1 | mg/ml | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 90.0 | % | 90 | % | DRUGBANK | |
| Bioavailability | 88.0 | % | 88 | % | DRUGBANK | |
| Metabolic | 15.0 | % | 10-20 | % | Active metabolite; | DRUGBANK |
| Clearance | 0.66 | L/h/kg | 11 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 1.8 | L/kg | 1.8±0.4 | L/kg | DRUGBANK | |
| Volume of Distribution | 1.8 | L/kg | 1.8 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 2.3 | h | 2.2-2.3 | h | elimination half-life; | DRUGBANK |
| Half-life | 2.7 | h | 2.6-2.8 | h | elimination half-life; | DRUGBANK |
| Half-life | 2.2 | h | 2.2 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route | 90.0 | % | >90 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 10.0 | % | ~10 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1