Basic Information

Drug ID DDPD09238 ...
Drug Name Manidipine
Molecular Weight 610.711
Molecular Formula C35H38N4O6
CAS Number 89226-50-6
SMILES COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)N(=O)=O)C(=O)OCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1
External Links
DRUGBANK DB09238
PubChem Compound 4008

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Water Solubility 1000.0 mg/L <1 mg/ml MSDS

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Tss 1.5 h 1.5 h DRUGBANK
Metabolic 5.5 % 4-7 % Urinary excretion; DRUGBANK
Metabolic 23.0 % 22-24 % Urinary excretion; DRUGBANK
Half-life 3.9 h 3.94 h DRUGBANK
Half-life 5.0 h 5.02 h DRUGBANK
Half-life 8.0 h 7.95 h DRUGBANK
Eliminate Route 63.0 % 63 % Faeces excretion; DRUGBANK
Eliminate Route 3.3 % 3.31 % Urinary excretion; DRUGBANK
Protein Binding 99.0 % 99 % plasma proteins; human, homo sapiens; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1