Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD09225 ...
Drug Name Zotepine
Molecular Weight 331.86
Molecular Formula C18H18ClNOS
CAS Number 26615-21-4
SMILES CN(C)CCOC1=CC2=CC=CC=C2SC2=CC=C(Cl)C=C12
External Links
DRUGBANK DB09225
PubChem Compound 5736

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 4.25 - 4.25 - 'MSDS'
Boiling Point 478.4 ℃ 478.4 ℃ 'MSDS'
Melting Point 90.0 ℃ 90 ℃ 'MSDS'

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Factor Reference
Absorption 100.0 % ~100 % PO, oral; DRUGBANK
C Max 13.3 ng/ml 6.9-19.6 ng/ml increasing doses; increasing doses ↑ ; DRUGBANK
T Max 3.0 h 2-4 h increasing doses; increasing doses ↑ ; DRUGBANK
Clearance 4.6 mg/h/kg 4.6 mg/h/kg apparent clearance; PO, oral; DRUGBANK
Volume of Distribution 109.0 L/kg 109.0 L/kg Apparent volume of distribution; DRUGBANK
Half-life 21.0 h 21 h DRUGBANK
Protein Binding 97.0 % 97 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1