Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.08 | - | 1.08 | - | Molbase |
| Boiling Point | 577.8 | ℃ | 577.8 | ℃ | 'MSDS' |
| Melting Point | 91.0 | ℃ | 91 | ℃ | 'MSDS' |
| pKa | 9.3 | - | 9.3 | - | Moffat, 1986 |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 88.0 | % | 88 | % | PO, oral; | DRUGBANK |
| AUC | 1670.0 | ng.h/ml | 1.67 | mg.h/l | PO, oral; | DRUGBANK |
| C Max | 26.3 | ng/ml | 26.3 | ng/ml | PO, oral; | DRUGBANK |
| T Max | 1.3 | h | 1.3 | h | PO, oral; | DRUGBANK |
| Metabolic | 1.0 | % | 1 | % | DRUGBANK | |
| Clearance | 7.6 | L/h | 126.0 | ml/min | PO, oral; | DRUGBANK |
| Volume of Distribution | 265.0 | L | 265.0 | L | one-compartment; | DRUGBANK | Volume of Distribution | 3207.0 | L | 3207.0 | L | two-compartment; | DRUGBANK |
| Half-life | 45.0 | h | 45 | h | PO, oral; | DRUGBANK | Half-life | 55.0 | h | 55 | h | PO, oral; | DRUGBANK | Half-life | 45.0 | h | 45 | h | PO, oral; | DRUGBANK |
| Protein Binding | 22.0 | % | 21-23 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1