Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.17 | - | 3.17 | - | United States Environmental Protection Agency. |
| Boiling Point | 371.0 | ℃ | 371 | ℃ | 'MSDS' |
| Melting Point | 145.0 | ℃ | 145 | ℃ | United States Environmental Protection Agency. |
| Water Solubility | 47.4 | mg/L | >47.4 | ug/ml | Burnham Center for Chemical Genomics |
| pKa | 8.71 | - | 8.71 | - | Microphysiology Database Project. University of Pittsburgh. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| AUC | 152600.0 | ng.h/ml | 152.6 | mg.h/l | intravenous injection, IV; | DRUGBANK |
| Bioavailability | 10.0 | % | 10 | % | DRUGBANK | |
| C Max | 352.8 | ng/ml | 352.8 | ng/ml | intravenous injection, IV; | DRUGBANK |
| Clearance | 0.43 | L/h/kg | 7.17 | ml/kg/min | Plasma clearance; dog; | DRUGBANK |
| Volume of Distribution | 0.91 | L/kg | 0.83-0.98 | L/kg | dog; | DRUGBANK |
| Half-life | 1.5 | h | 1-2 | h | DRUGBANK | |
| Eliminate Route | 69.0 | % | 69 | % | Urinary excretion; PO, oral; | DRUGBANK | Eliminate Route | 14.0 | % | 14 | % | Faeces excretion; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1