Basic Information

Drug ID DDPD09121 ...
Drug Name Aurothioglucose
Molecular Weight 392.18
Molecular Formula C6H11AuO5S
CAS Number 12192-57-3
SMILES OC[C@H]1O[C@H](S[Au])[C@H](O)[C@@H](O)[C@@H]1O
External Links
DRUGBANK DB09121
PubChem Compound 6104

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Factor Reference
C Max 3425000000.0 ng/ml 342.5 g/dl DRUGBANK
T Max 5.0 h 4-6 h IM,intramuscular injection; DRUGBANK
Half-life 360.0 h ~3-27 day elimination half-life; Single dose; dose ↑ ; DRUGBANK
Half-life 648.0 h 14-40 day DRUGBANK
Half-life 4032.0 h 168 day DRUGBANK
Toxicity TDLo 3.4 mg/kg ~3.357 mg/kg IM,intramuscular injection; Male, men; DRUGBANK
Toxicity TDLo 5.5 mg/kg ~5.5 mg/kg IM,intramuscular injection; Male, men; DRUGBANK
Toxicity TDLo 2.7 mg/kg 2.6-2.7 mg/kg IM,intramuscular injection;  Female, women; cholestatic jaundice; DRUGBANK
Toxicity TDLo 14.4 mg/kg ~14.402 mg/kg IM,intramuscular injection;  Female, women; acute renal failure; acute tubular necrosis; DRUGBANK
Eliminate Route 70.0 % ~70 % Urinary excretion; IM,intramuscular injection; patients; human, homo sapiens; DRUGBANK
Eliminate Route 30.0 % ~30 % Faeces excretion; IM,intramuscular injection; patients; human, homo sapiens; DRUGBANK
Protein Binding 97.0 % 95-99 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

...

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1