Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD09097 ...
Drug Name Quinagolide
Molecular Weight 395.56
Molecular Formula C20H33N3O3S
CAS Number 87056-78-8
SMILES [H][C@]12C[C@@H](CN(CCC)[C@]1([H])CC1=CC=CC(O)=C1C2)NS(=O)(=O)N(CC)CC
External Links
DRUGBANK DB09097
PubChem Compound 3086401

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 234.0 ℃ 231-237 ℃ FDA Label/Product monograph
Water Solubility 0.2 % 0.2 % FDA Label/Product monograph

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Absorption 95.0 % 95 % PO, oral; DRUGBANK
Bioavailability 4.0 % 4 % PO, oral; DRUGBANK
T Max 0.75 h 0.5-1 h PO, oral; DRUGBANK
Volume of Distribution 100.0 L ~100 L DRUGBANK
Half-life 11.5 h 11.5 h terminal half-life; Single dose; DRUGBANK
Half-life 17.0 h 17 h at steady state; DRUGBANK
Toxicity LD50 300.0 mg/kg 300.0 mg/kg PO, oral; mouse; DRUGBANK
Toxicity LD50 980.0 mg/kg 980.0 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Toxicity LD50 3200.0 mg/kg 3200.0 mg/kg PO, oral; rabbit; DRUGBANK
Eliminate Route 50.0 % 50 % Urinary excretion; DRUGBANK
Protein Binding 90.0 % ~90 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1