Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD09093 ...
Drug Name Chlortetracycline
Molecular Weight 478.88
Molecular Formula C22H23ClN2O8
CAS Number 57-62-5
SMILES [H][C@@]12C[C@@]3([H])C(=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C)C(=O)C1=C(O)C=CC(Cl)=C1[C@@]3(C)O
External Links
DRUGBANK DB09093
PubChem Compound 54708735

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 212.5 ℃ 210-215 ℃ MSDS

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 22.5 % 15-30 % DRUGBANK
T Max 3.0 h 3 h DRUGBANK
Clearance 0.12 L/h/kg 2 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 100.0 L 100.0 L DRUGBANK
Volume of Distribution 0.90 L/kg 0.9 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 5.6 h 5.6 h DRUGBANK
Half-life 7.0 h 7 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Toxicity LD50 2314.0 mg/kg 2314.0 mg/kg PO, oral; mouse; DRUGBANK
Protein Binding 52.5 % 50-55 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1