Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 80.0 | ℃ | 78-82 | ℃ | Product monograph |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 1.0 | h | 1 | h | PO, oral; Derivative; | DRUGBANK | T Max | 0.80 | h | 0.8 | h | Oral single dose; | DRUGBANK |
| Half-life | 1.0 | h | ~1 | h | elimination half-life; Oral single dose; | DRUGBANK | Half-life | 2.8 | h | 2.77 | h | Oral single dose; | DRUGBANK |
| Toxicity LD50 | 5000.0 | mg/kg | >5000 | mg/kg | PO, oral; mouse; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 2500.0 | mg/kg | 2500.0 | mg/kg | PO, oral; rabbit; | DRUGBANK |
| Eliminate Route | 8.5 | % | 5-12 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 94.0 | % | ~94 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 2.4 | % | <2.4 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
| Protein Binding | 5.0 | % | 5 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1