| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Factor |
Reference |
| Bioavailability |
30.0 |
% |
~30 |
% |
inhalation, IH; normal,healthy; |
|
DRUGBANK |
Bioavailability |
1.0 |
% |
<1 |
% |
Liquid; |
|
DRUGBANK |
| T Max |
0.25 |
h |
10-20 |
min |
inhalation, IH; |
|
DRUGBANK |
| Clearance |
52.3 |
L/h |
872.0 |
ml/min |
Total clearance; normal,healthy; |
|
DRUGBANK |
Clearance |
10.4 |
L/h |
173.0 |
ml/min |
Renal clearance; normal,healthy; |
|
DRUGBANK |
Clearance |
0.75 |
L/h/kg |
12.45 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
1110.0 |
L |
1110.0 |
L |
|
|
DRUGBANK |
Volume of Distribution |
15.9 |
L/kg |
15.85 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
22.0 |
h |
22 |
h |
terminal half-life; intravenous injection, IV; |
|
DRUGBANK |
Half-life |
45.0 |
h |
~45 |
h |
terminal half-life; inhalation, IH; |
|
DRUGBANK |
Half-life |
22.1 |
h |
22.1 |
h |
intravenous injection, IV; human, homo sapiens; |
|
Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route |
38.0 |
% |
38 |
% |
Urinary excretion; intravenous injection, IV; |
|
DRUGBANK |
Eliminate Route |
53.0 |
% |
53 |
% |
Faeces excretion; intravenous injection, IV; |
|
DRUGBANK |
Eliminate Route |
9.0 |
% |
9 |
% |
Urinary excretion; PO, oral; |
|
DRUGBANK |
Eliminate Route |
84.0 |
% |
84 |
% |
Faeces excretion; PO, oral; |
|
DRUGBANK |
Eliminate Route |
19.0 |
% |
19 |
% |
Urinary excretion; intravenous injection, IV; Unchanged drug; |
|
DRUGBANK |
Eliminate Route |
9.0 |
% |
<9 |
% |
Urinary excretion; PO, oral; Unchanged drug; |
|
DRUGBANK |
| Protein Binding |
60.0 |
% |
~60 |
% |
plasma proteins; high protein binding; human, homo sapiens; |
Plasma Concentration → ; |
DRUGBANK |
