Basic Information
| Drug ID | DDPD09076 |
|
| Drug Name | Umeclidinium | |
| Molecular Weight | 428.595 | |
| Molecular Formula | C29H34NO2 | |
| CAS Number | 869185-19-3 | |
| SMILES | OC(C1=CC=CC=C1)(C1=CC=CC=C1)C12CC[N+](CCOCC3=CC=CC=C3)(CC1)CC2 | |
| External Links | ||
| DRUGBANK | DB09076 | |
| PubChem Compound | 11519070 | |
| PDR | 3546 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 0.17 | h | 5-15 | min | DRUGBANK | |
| Tss | 336.0 | h | 14 | day | DRUGBANK | |
| Clearance | 2.2 | L/h/kg | 35.95 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 86.0 | L | 86.0 | L | Average volume of distribution; | DRUGBANK | Volume of Distribution | 1.2 | L/kg | 1.23 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 11.0 | h | 11 | h | effective half-life; Multiple dose; | DRUGBANK | Half-life | 19.0 | h | 19 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route | 58.0 | % | 58 | % | Faeces excretion; intravenous injection, IV; | DRUGBANK | Eliminate Route | 22.0 | % | 22 | % | Urinary excretion; intravenous injection, IV; | DRUGBANK |
| Protein Binding | 89.0 | % | 89 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 0.0625 | mg/day | 62.5 | mcg/day | inhalation, IH | Incruse Ellipta | umeclidinium | PDR |
| Max dose for geriatric | 0.0625 | mg/day | 62.5 | mcg/day | inhalation, IH | Incruse Ellipta | umeclidinium | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1