Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
Clearance |
0.54 |
L/h/kg |
9.04 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution |
91.0 |
L |
56-126 |
L |
Apparent volume of distribution; at steady state; PO, oral; normal,healthy; young; |
DRUGBANK |
Volume of Distribution |
0.33 |
L/kg |
0.33 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Half-life |
1.3 |
h |
1.3±0.4 |
h |
elimination half-life; |
DRUGBANK |
Half-life |
0.75 |
h |
0.75 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Eliminate Route |
80.0 |
% |
80 |
% |
Urinary excretion; PO, oral; |
DRUGBANK |
Eliminate Route |
4.0 |
% |
~4 |
% |
Faeces excretion; PO, oral; |
DRUGBANK |
Protein Binding |
90.0 |
% |
90 |
% |
|
DRUGBANK |