Basic Information

Drug ID DDPD09071 ...
Drug Name Tasimelteon
Molecular Weight 245.322
Molecular Formula C15H19NO2
CAS Number 609799-22-6
SMILES CCC(=O)NC[C@@H]1C[C@H]1C1=CC=CC2=C1CCO2
External Links
DRUGBANK DB09071
PubChem Compound 10220503
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 2.43 - 2.43 - MSDS
Boiling Point 442.553 442.553 MSDS
Water Solubility 1100.0 mg/L 1.1 mg/ml MSDS

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.54 L/h/kg 9.04 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 91.0 L 56-126 L Apparent volume of distribution; at steady state; PO, oral; normal,healthy; young; DRUGBANK
Volume of Distribution 0.33 L/kg 0.33 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 1.3 h 1.3±0.4 h elimination half-life; DRUGBANK
Half-life 0.75 h 0.75 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Eliminate Route 80.0 % 80 % Urinary excretion; PO, oral; DRUGBANK
Eliminate Route 4.0 % ~4 % Faeces excretion; PO, oral; DRUGBANK
Protein Binding 90.0 % 90 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1