DETAILS

Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID	DDPD09070
Drug Name	Tibolone
Molecular Weight	312.453
Molecular Formula	C21H28O2
CAS Number	5630-53-5
SMILES	[H][C@@]12CC[C@@](O)(C#C)[C@@]1(C)CC[C@]1([H])C3=C(CC(=O)CC3)C[C@@]([H])(C)[C@@]21[H]
External Links
	DRUGBANK	DB09070
	PubChem Compound	444008

Experimental Physicochemical Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Reference
Water Solubility	100.0	mg/L	<0.1	g/L	MSDS

Pharmacokinetic/ Toxicokinetic Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Reference
T Max	1.3	h	1-1.5	h	PO, oral; Active metabolite;	DRUGBANK
Half-life	45.0	h	~45	h	elimination half-life;	DRUGBANK
Toxicity LD50	2000.0	mg/kg	>2000	mg/kg		DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1