Basic Information
| Drug ID | DDPD09068 |
|
| Drug Name | Vortioxetine | |
| Molecular Weight | 298.45 | |
| Molecular Formula | C18H22N2S | |
| CAS Number | 508233-74-7 | |
| SMILES | CC1=CC=C(SC2=CC=CC=C2N2CCNCC2)C(C)=C1 | |
| External Links | ||
| DRUGBANK | DB09068 | |
| PubChem Compound | 71768094 | |
| PDR | 3348 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 9.0 | h | 7-11 | h | DRUGBANK | |
| Clearance | 0.35 | L/h/kg | 5.8 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 2600.0 | L | ~2600 | L | Apparent volume of distribution; | DRUGBANK | Volume of Distribution | 35.3 | L/kg | 35.3 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 66.0 | h | ~66 | h | terminal half-life; | DRUGBANK | Half-life | 72.0 | h | 72 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 98.0 | % | 98 | % | plasma proteins; human, homo sapiens; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 20.0 | mg/day | 20 | mg/day | PO, oral | Trintellix | vortioxetine | PDR |
| Max dose for geriatric | 20.0 | mg/day | 20 | mg/day | PO, oral | Trintellix | vortioxetine | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1