Basic Information
| Drug ID | DDPD09060 |
|
| Drug Name | Avibactam | |
| Molecular Weight | 265.24 | |
| Molecular Formula | C7H11N3O6S | |
| CAS Number | 1192500-31-4 | |
| SMILES | NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(O)(=O)=O | |
| External Links | ||
| DRUGBANK | DB09060 | |
| PubChem Compound | 9835049 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 85.0 | % | 80-90 | % | Urinary excretion; Unchanged drug; | DRUGBANK |
| Clearance | 12.0 | L/h | ~12 | L/h | DRUGBANK | Clearance | 0.17 | L/h/kg | 2.76 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 22.2 | L | 22.2 | L | Steady state volume of distribution; | DRUGBANK | Volume of Distribution | 0.24 | L/kg | 0.24 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 2.9 | h | ~2.7-3.0 | h | DRUGBANK | Half-life | 1.7 | h | 1.7 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 7.0 | % | 5.7-8.2 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1