Basic Information
| Drug ID | DDPD09054 |
|
| Drug Name | Idelalisib | |
| Molecular Weight | 415.432 | |
| Molecular Formula | C22H18FN7O | |
| CAS Number | 870281-82-6 | |
| SMILES | [H][C@@](CC)(NC1=NC=NC2=C1N=CN2)C1=NC2=CC=CC(F)=C2C(=O)N1C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB09054 | |
| PubChem Compound | 11625818 | |
| PDR | 3545 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Factor | Reference |
|---|---|---|---|---|---|---|---|
| T Max | 1.5 | h | 1.5 | h | PO, oral; | DRUGBANK | |
| Clearance | 14.9 | L/h | 14.9 | L/h | DRUGBANK | ||
| Volume of Distribution | 23.0 | L | 23.0 | L | DRUGBANK | ||
| Half-life | 8.2 | h | 8.2 | h | elimination half-life; | DRUGBANK | |
| Eliminate Route | 78.0 | % | 78 | % | Faeces excretion; Single dose; | DRUGBANK | Eliminate Route | 14.0 | % | 14 | % | Urinary excretion; Single dose; | DRUGBANK |
| Protein Binding | 84.0 | % | >84 | % | plasma proteins; human, homo sapiens; | Plasma Concentration → ; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Frequency | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 300.0 | mg/day | 150 | mg/dose | PO, oral | bid | Zydelig | idelalisib | PDR |
| Max dose for geriatric | 300.0 | mg/day | 150 | mg/dose | PO, oral | bid | Zydelig | idelalisib | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1