Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD08918 ...
Drug Name Levomilnacipran
Molecular Weight 246.348
Molecular Formula C15H22N2O
CAS Number 96847-54-0
SMILES CCN(CC)C(=O)[C@]1(C[C@H]1CN)C1=CC=CC=C1
External Links
DRUGBANK DB08918
PubChem Compound 6917779
PDR 3303

Experimental Physicochemical Property

Not Available

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
AUC 5196.0 ng.h/ml 5196.0 ng.h/ml Capsule, PO, Oral; extended release formulation; DRUGBANK
C Max 341.0 ng/ml 341 ng/ml Capsule, PO, Oral; extended release formulation; DRUGBANK
T Max 7.0 h 6-8 h PO, oral; DRUGBANK
Clearance 25.0 L/h 21-29 L/h apparent clearance; DRUGBANK
Volume of Distribution 430.0 L 387-473 L Apparent volume of distribution; DRUGBANK
Half-life 12.0 h 12 h DRUGBANK
Eliminate Route 58.0 % 58 % Urinary excretion; Unchanged drug; DRUGBANK
Protein Binding 22.0 % 22 % plasma proteins; human, homo sapiens; DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for adults 120.0 mg/day 120 mg/day PO, oral Fetzima levomilnacipran PDR
Max dose for geriatric 120.0 mg/day 120 mg/day PO, oral Fetzima levomilnacipran PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1