Basic Information
| Drug ID | DDPD08913 |
|
| Drug Name | Radium Ra 223 dichloride | |
| Molecular Weight | 293.924 | |
| Molecular Formula | Cl2Ra | |
| CAS Number | 444811-40-9 | |
| SMILES | [Cl-].[Cl-].[223Ra++] | |
| External Links | ||
| DRUGBANK | DB08913 | |
| PDR | 3180 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 100.0 | % | 100 | % | intravenous injection, IV; | DRUGBANK |
| Half-life | 273.6 | h | 11.4 | day | DRUGBANK | |
| Eliminate Route | 13.0 | % | 13 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 2.0 | % | 2 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 0 | % | ~0 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 1.49 | microcurie/kg | 1.49 | microcurie/kg | Xofigo | radium Ra 223 dichloride | PDR | |
| Max dose for adults | 55.0 | kBq/kg | 55 | kBq/kg | Xofigo | radium Ra 223 dichloride | PDR | |
| Max dose for geriatric | 0.00149 | mg/kg | 1.49 | microcurie/kg | Xofigo | radium Ra 223 dichloride | PDR | |
| Max dose for geriatric | 55.0 | kBq/kg | 55 | kBq/kg | Xofigo | radium Ra 223 dichloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1