| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Factor |
Reference |
| AUC |
400.0 |
ng.h/ml |
400.0 |
ng.h/ml |
PO, oral; multiple myeloma; |
|
DRUGBANK |
| C Max |
75.0 |
ng/ml |
75 |
ng/ml |
PO, oral; multiple myeloma; |
|
DRUGBANK |
| T Max |
2.5 |
h |
2-3 |
h |
Oral single dose; |
|
DRUGBANK |
| Clearance |
8.5 |
L/h |
7.0-10 |
L/h |
Total clearance; |
|
DRUGBANK |
| Volume of Distribution |
100.0 |
L |
62-138 |
L |
Apparent volume of distribution; at steady state; |
|
DRUGBANK |
| Half-life |
9.4 |
h |
9.4 |
h |
normal,healthy; |
|
DRUGBANK |
Half-life |
7.5 |
h |
7.5 |
h |
multiple myeloma; patients; |
|
DRUGBANK |
| Eliminate Route |
73.0 |
% |
73 |
% |
Urinary excretion; Oral single dose; normal,healthy; human, homo sapiens; |
|
DRUGBANK |
Eliminate Route |
15.0 |
% |
15 |
% |
Faeces excretion; Oral single dose; normal,healthy; human, homo sapiens; |
|
DRUGBANK |
Eliminate Route |
2.0 |
% |
2 |
% |
Urinary excretion; PO, oral; Unchanged drug; |
|
DRUGBANK |
Eliminate Route |
8.0 |
% |
8 |
% |
Faeces excretion; PO, oral; Unchanged drug; |
|
DRUGBANK |
| Protein Binding |
28.0 |
% |
12-44 |
% |
|
Plasma Concentration → ; |
DRUGBANK |
