Basic Information
| Drug ID | DDPD08908 |
|
| Drug Name | Dimethyl fumarate | |
| Molecular Weight | 144.1253 | |
| Molecular Formula | C6H8O4 | |
| CAS Number | 624-49-7 | |
| SMILES | [H]\C(=C(\[H])C(=O)OC)C(=O)OC | |
| External Links | ||
| DRUGBANK | DB08908 | |
| PubChem Compound | 637568 | |
| PDR | 3095 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Boiling Point | 192.5 | ℃ | 192-193 | ℃ | From MSDS. |
| Melting Point | 103.5 | ℃ | 103-104 | ℃ | From MSDS. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| C Max | 1870.0 | ng/ml | 1.87 | mg/L | Active metabolite; | DRUGBANK |
| T Max | 2.5 | h | 2.5 | h | Active metabolite; | DRUGBANK |
| Volume of Distribution | 63.0 | L | 53-73 | L | normal,healthy; | DRUGBANK |
| Half-life | 1.0 | h | ~1 | h | DRUGBANK | |
| Eliminate Route | 60.0 | % | 60 | % | lung excretion; | DRUGBANK | Eliminate Route | 16.0 | % | 16 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 1.0 | % | 1 | % | Faeces excretion; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 480.0 | mg/day | 480 | mg/day | PO, oral | Tecfidera | dimethyl fumarate | PDR |
| Max dose for geriatric | 480.0 | mg/day | 480 | mg/day | PO, oral | Tecfidera | dimethyl fumarate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1