| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| Bioavailability |
0.50 |
% |
0.50 |
% |
intranasal; |
DRUGBANK |
Bioavailability |
1.3 |
% |
1.26 |
% |
PO, oral; |
DRUGBANK |
Bioavailability |
13.9 |
% |
13.9 |
% |
inhalation, IH; |
DRUGBANK |
Bioavailability |
12.4 |
% |
6.3-18.4 |
% |
inhalation, IH; normal,healthy; postmenopausal women; |
DRUGBANK |
| Clearance |
57.8 |
L/h |
57.8 |
L/h |
|
DRUGBANK |
Clearance |
71.8 |
L/h |
71.8 |
L/h |
intravenous injection, IV; normal,healthy; Caucasian; Male, men; |
DRUGBANK |
Clearance |
0.80 |
L/h/kg |
13.4 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution |
608.0 |
L |
608.0 |
L |
at steady state; intravenous injection, IV; |
DRUGBANK |
Volume of Distribution |
661.0 |
L |
661.0 |
L |
Average volume of distribution; at steady state; |
DRUGBANK |
Volume of Distribution |
704.0 |
L |
704.0 |
L |
at steady state; intravenous injection, IV; normal,healthy; Caucasian; Male, men; |
DRUGBANK |
Volume of Distribution |
5.0 |
L/kg |
4.95 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Half-life |
15.1 |
h |
15.1 |
h |
intranasal; |
DRUGBANK |
Half-life |
24.0 |
h |
24 |
h |
inhalation, IH; |
DRUGBANK |
Half-life |
13.6 |
h |
13.6 |
h |
intravenous injection, IV; normal,healthy; Caucasian; Male, men; |
DRUGBANK |
Half-life |
20.6 |
h |
17.3-23.9 |
h |
inhalation, IH; normal,healthy; Caucasian; Male, men; |
DRUGBANK |
Half-life |
10.6 |
h |
10.6 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route |
90.0 |
% |
≥90 |
% |
Faeces excretion; |
DRUGBANK |
Eliminate Route |
1.5 |
% |
1-2 |
% |
Urinary excretion; |
DRUGBANK |
| Protein Binding |
99.0 |
% |
>99 |
% |
|
DRUGBANK |
