Basic Information
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| AUC | 64750.0 | ng.h/ml | 64.75 | ug.h/ml | PO, oral; | DRUGBANK |
| C Max | 5500.0 | ng/ml | 5.5 | ug/ml | PO, oral; | DRUGBANK |
| T Max | 5.0 | h | 5 | h | PO, oral; | DRUGBANK |
| Volume of Distribution | 164.0 | L | 164.0 | L | Total volume of distribution; | DRUGBANK |
| Half-life | 3960.0 | h | 5.5 | month | elimination half-life; | DRUGBANK | Half-life | 3960.0 | h | 5.5 | month | elimination half-life; | DRUGBANK |
| Protein Binding | 99.9 | % | >99.9 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 400.0 | mg/day | 400 | mg/day | PO, oral | Sirturo | bedaquiline | PDR |
| Max dose for children | 200.0 | mg/day | 200 | mg/day | PO, oral | Sirturo | bedaquiline | PDR |
| Max dose for adolescents | 400.0 | mg/day | 400 | mg/day | PO, oral | Sirturo | bedaquiline | PDR |
| Max dose for adolescents | 200.0 | mg/day | 200 | mg/day | PO, oral | Sirturo | bedaquiline | PDR |
| Max dose for adults | 400.0 | mg/day | 400 | mg/day | PO, oral | Sirturo | bedaquiline | PDR |
| Max dose for geriatric | 400.0 | mg/day | 400 | mg/day | PO, oral | Sirturo | bedaquiline | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1