Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
Bioavailability |
29.0 |
% |
29 |
% |
PO, oral; |
DRUGBANK |
Bioavailability |
35.0 |
% |
35 |
% |
PO, oral; |
DRUGBANK |
T Max |
3.5 |
h |
3.5 |
h |
PO, oral; normal,healthy; |
DRUGBANK |
Tss |
168.0 |
h |
7 |
day |
PO, oral; |
DRUGBANK |
Clearance |
57.0 |
L/h |
57.0 |
L/h |
Total clearance; intravenous injection, IV; |
DRUGBANK |
Clearance |
13.0 |
L/h |
13.0 |
L/h |
Renal clearance; |
DRUGBANK |
Clearance |
0.82 |
L/h/kg |
13.6 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution |
1670.0 |
L |
1670.0 |
L |
at steady state; intravenous injection, IV; |
DRUGBANK |
Volume of Distribution |
23.8 |
L/kg |
23.8 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Half-life |
50.0 |
h |
50 |
h |
elimination half-life; |
DRUGBANK |
Half-life |
50.0 |
h |
50 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Eliminate Route |
55.0 |
% |
55 |
% |
Urinary excretion; |
DRUGBANK |
Eliminate Route |
34.0 |
% |
34 |
% |
Faeces excretion; |
DRUGBANK |
Eliminate Route |
25.0 |
% |
~25 |
% |
Urinary excretion; Unchanged drug; |
DRUGBANK |
Eliminate Route |
0 |
% |
0 |
% |
Faeces excretion; Unchanged drug; |
DRUGBANK |
Protein Binding |
71.0 |
% |
71 |
% |
plasma proteins; |
DRUGBANK |