Basic Information
| Drug ID | DDPD08874 |
|
| Drug Name | Fidaxomicin | |
| Molecular Weight | 1058.05 | |
| Molecular Formula | C52H74Cl2O18 | |
| CAS Number | 873857-62-6 | |
| SMILES | [H][C@@]1(O[C@@H]2[C@@H](CC)\C=C(C)\[C@@H](O)C\C=C\C=C(CO[C@@H]3O[C@H](C)[C@@H](OC(=O)C4=C(CC)C(Cl)=C(O)C(Cl)=C4O)[C@H](O)[C@@H]3OC)\C(=O)O[C@@H](C\C=C(/C)\C=C2/C)[C@@H](C)O)OC(C)(C)[C@@H](OC(=O)C(C)C)[C@H](O)[C@@H]1O | |
| External Links | ||
| DRUGBANK | DB08874 | |
| PubChem Compound | 70678896 | |
| PDR | 460 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Boiling Point | 1046.4 | ℃ | 1046.4 | ℃ | MSDS (Santa Cruz Biotechnology) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| C Max | 5.2 | ng/ml | 5.20±2.81 | ng/ml | PO, oral; normal,healthy; adults; | DRUGBANK | C Max | 12.0 | ng/ml | 12.0±6.06 | ng/ml | PO, oral; normal,healthy; adults; Active metabolite; | DRUGBANK |
| T Max | 2.0 | h | 2 | h | DRUGBANK | |
| Half-life | 11.7 | h | 11.7±4.80 | h | normal,healthy; adults; Oral single dose; | DRUGBANK |
| Toxicity LD50 | 200.0 | mg/kg | ~200 | mg/kg | Rattus, Rat; | DRUGBANK |
| Toxicity NOAEL | 62.5 | mg/kg | 62.5 | mg/kg | Rattus, Rat; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 400.0 | mg/day | 400 | mg/day | PO, oral | Dificid | fidaxomicin | PDR |
| Max dose for geriatric | 400.0 | mg/day | 400 | mg/day | PO, oral | Dificid | fidaxomicin | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1