Basic Information
| Drug ID | DDPD08873 |
|
| Drug Name | Boceprevir | |
| Molecular Weight | 519.6767 | |
| Molecular Formula | C27H45N5O5 | |
| CAS Number | 394730-60-0 | |
| SMILES | [H][C@]12CN([C@H](C(=O)NC(CC3CCC3)C(=O)C(N)=O)[C@@]1([H])C2(C)C)C(=O)[C@@H](NC(=O)NC(C)(C)C)C(C)(C)C | |
| External Links | ||
| DRUGBANK | DB08873 | |
| PubChem Compound | 10324367 | |
| PDR | 398 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 2.0 | h | 2 | h | DRUGBANK | |
| Clearance | 161.0 | L/h | 161.0 | L/h | Average clearance; | DRUGBANK |
| Volume of Distribution | 772.0 | L | 772.0 | L | Apparent volume of distribution; at steady state; | DRUGBANK |
| Half-life | 3.4 | h | 3.4 | h | DRUGBANK | |
| Eliminate Route | 79.0 | % | 79 | % | Faeces excretion; | DRUGBANK |
| Eliminate Route | 9.0 | % | 9 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 75.0 | % | ~75 | % | plasma proteins; Single dose; human, homo sapiens; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 2400.0 | mg/day | 2400 | mg/day | PO, oral | Victrelis | boceprevir | PDR |
| Max dose for geriatric | 2400.0 | mg/day | 2400 | mg/day | PO, oral | Victrelis | boceprevir | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1