Basic Information
| Drug ID | DDPD08872 |
|
| Drug Name | Gabapentin enacarbil | |
| Molecular Weight | 329.393 | |
| Molecular Formula | C16H27NO6 | |
| CAS Number | 478296-72-9 | |
| SMILES | CC(C)C(=O)OC(C)OC(=O)NCC1(CC(O)=O)CCCCC1 | |
| External Links | ||
| DRUGBANK | DB08872 | |
| PubChem Compound | 9883933 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 64.0 | ℃ | ~64 | ℃ | From FDA label. |
| Water Solubility | 500.0 | mg/L | 0.5 | mg/ml | From FDA label. |
| pKa | 5.0 | - | 5 | - | From The Merck Index. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 6.0 | L/h | 5.0-7 | L/h | Renal clearance; | DRUGBANK |
| Volume of Distribution | 76.0 | L | 76.0 | L | DRUGBANK | |
| Half-life | 5.6 | h | 5.1-6.0 | h | elimination half-life; | DRUGBANK |
| Eliminate Route | 94.0 | % | 94 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 5.0 | % | 5 | % | Faeces excretion; | DRUGBANK |
| Protein Binding | 3.0 | % | <3 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1