Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
Bioavailability |
43.0 |
% |
43 |
% |
Oral single dose; |
DRUGBANK |
T Max |
5.0 |
h |
4-6 |
h |
Oral single dose; |
DRUGBANK |
Tss |
360.0 |
h |
15 |
day |
PO, oral; |
DRUGBANK |
Clearance |
0.59 |
L/h/kg |
9.75 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution |
1772.0 |
L |
1772.0 |
L |
Average volume of distribution; intravenous injection, IV; |
DRUGBANK |
Volume of Distribution |
22.2 |
L/kg |
22.15 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Half-life |
42.0 |
h |
42 |
h |
terminal half-life; patients; |
DRUGBANK |
Half-life |
38.9 |
h |
38.9 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Eliminate Route |
63.0 |
% |
63 |
% |
Faeces excretion; Single dose; normal,healthy; human, homo sapiens; |
DRUGBANK |
Eliminate Route |
22.0 |
% |
22 |
% |
Urinary excretion; Single dose; normal,healthy; human, homo sapiens; |
DRUGBANK |
Eliminate Route |
53.0 |
% |
53 |
% |
Faeces excretion; Unchanged drug; |
DRUGBANK |
Eliminate Route |
2.3 |
% |
2.3 |
% |
Urinary excretion; Unchanged drug; |
DRUGBANK |
Protein Binding |
91.0 |
% |
91 |
% |
plasma proteins; |
DRUGBANK |