Basic Information
| Drug ID | DDPD08826 |
|
| Drug Name | Deferiprone | |
| Molecular Weight | 139.1519 | |
| Molecular Formula | C7H9NO2 | |
| CAS Number | 30652-11-0 | |
| SMILES | CN1C=CC(=O)C(O)=C1C | |
| External Links | ||
| DRUGBANK | DB08826 | |
| PubChem Compound | 2972 | |
| PDR | 2450 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 275.0 | ℃ | 272-278 | ℃ | DRUGBANK |
| Water Solubility | 17000.0 | mg/L | 16-18 | g/L | DRUGBANK |
| pKa | 3.5 | - | 3.5 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 1.0 | h | 1 | h | PO, oral; fasting; | DRUGBANK | T Max | 2.0 | h | 2 | h | PO, oral; food; | DRUGBANK |
| Volume of Distribution | 1.0 | L/kg | 1.0 | L/kg | normal,healthy; patients; | DRUGBANK | Volume of Distribution | 1.6 | L/kg | 1.6 | L/kg | thalassemia; patients; | DRUGBANK |
| Half-life | 1.9 | h | 1.9 | h | DRUGBANK | |
| Protein Binding | 10.0 | % | <10 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for neonates | 0.0 | 0 | Ferriprox Tablets | deferiprone | PDR | |||
| Max dose for infants | 0.0 | 0 | Ferriprox Tablets | deferiprone | PDR | |||
| Max dose for adults | 99.0 | mg/kg/day | 99 | mg/kg/day | PO, oral | Ferriprox Tablets | deferiprone | PDR |
| Max dose for geriatric | 99.0 | mg/kg/day | 99 | mg/kg/day | PO, oral | Ferriprox Tablets | deferiprone | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1