Basic Information
| Drug ID | DDPD08815 |
|
| Drug Name | Lurasidone | |
| Molecular Weight | 492.676 | |
| Molecular Formula | C28H36N4O2S | |
| CAS Number | 367514-87-2 | |
| SMILES | [H][C@@]12[C@H]3CC[C@H](C3)[C@]1([H])C(=O)N(C[C@@H]1CCCC[C@H]1CN1CCN(CC1)C1=NSC3=CC=CC=C13)C2=O | |
| External Links | ||
| DRUGBANK | DB08815 | |
| PubChem Compound | 213046 | |
| PDR | 553 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 14.0 | % | 9-19 | % | DRUGBANK | |
| T Max | 2.5 | h | 1-4 | h | DRUGBANK | T Max | 3.5 | h | 1.5-5.5 | h | PO, oral; food; | DRUGBANK |
| Clearance | 234.1 | L/h | 3902.0 | ml/min | DRUGBANK | |
| Volume of Distribution | 6173.0 | L | 6173.0 | L | DRUGBANK | |
| Half-life | 18.0 | h | 18 | h | DRUGBANK | Half-life | 33.0 | h | 29-37 | h | DRUGBANK |
| Eliminate Route | 9.0 | % | ~9 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 80.0 | % | ~80 | % | Faeces excretion; | DRUGBANK |
| Protein Binding | 99.0 | % | ~99 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 80.0 | mg/day | 80 | mg/day | PO, oral | Latuda | lurasidone hydrochloride | PDR |
| Max dose for adolescents | 80.0 | mg/day | 80 | mg/day | PO, oral | Latuda | lurasidone hydrochloride | PDR |
| Max dose for adults | 160.0 | mg/day | 160 | mg/day | PO, oral | Latuda | lurasidone hydrochloride | PDR |
| Max dose for geriatric | 160.0 | mg/day | 160 | mg/day | PO, oral | Latuda | lurasidone hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1