Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD08814 ...
Drug Name Triflusal
Molecular Weight 248.157
Molecular Formula C10H7F3O4
CAS Number 322-79-2
SMILES CC(=O)OC1=C(C=CC(=C1)C(F)(F)F)C(O)=O
External Links
DRUGBANK DB08814
PubChem Compound 9458

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 2.231 - 2.231 - 'MSDS'
Melting Point 115.5 ℃ 114-117 ℃ 'MSDS'
Water Solubility 1000.0 mg/L <1 mg/ml 'MSDS'

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 91.5 % 83-100 % DRUGBANK
C Max 11600.0 ng/ml 11.6 mcg/ml DRUGBANK
C Max 92700.0 ng/ml 92.7 mcg/ml DRUGBANK
T Max 0.88 h 0.88 h DRUGBANK
T Max 5.0 h 4.96 h DRUGBANK
Clearance 0.80 L/h 0.8±0.2 L/h Renal clearance; DRUGBANK
Clearance 0.18 L/h 0.18±1 0.04 L/h Renal clearance; Drug combination; DRUGBANK
Volume of Distribution 34.0 L 34.0 L DRUGBANK
Half-life 0.50 h 0.5±0.1 h DRUGBANK
Half-life 34.3 h 34.3±5.3 h Metabolite; DRUGBANK
Protein Binding 99.0 % 99 % plasma proteins; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1