Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.92 | - | 0.92 | - | HANSCH,C ET AL. (1995) |
| Boiling Point | 194.0 | ℃ | 194 | ℃ | PhysProp |
| Melting Point | 13.5 | ℃ | 13.5 | ℃ | PhysProp |
| Water Solubility | 1000000.0 | mg/L | 1000000 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 1.26 | - | 1.26 | - | MARUTHAMUTHU,P & HUIE,RE (1995) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.32 | L/h/kg | 5.3 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.19 | L/kg | 0.19 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 0.65 | h | 0.65 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 2820.0 | mg/kg | 2820.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 510.0 | mg/kg | 510.0 | mg/kg | skin/dermal; rabbit; | DRUGBANK | Toxicity LD50 | 2820.0 | mg/kg | 2820.0 | mg/kg | PO, oral; Rattus, Rat; | T3DB | Toxicity LD50 | 510.0 | mg/kg | 510.0 | mg/kg | skin/dermal; rabbit; | T3DB |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1