Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD08801 ...
Drug Name Dimetindene
Molecular Weight 292.418
Molecular Formula C20H24N2
CAS Number 5636-83-9
SMILES CC(C1=C(CCN(C)C)CC2=CC=CC=C12)C1=CC=CC=N1
External Links
DRUGBANK DB08801
PubChem Compound 21855

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Melting Point 158.0 ℃ 158 ℃ Huebner, C.F.; U S . Patent 2,970,149; January 31, 1961; assigned to Ciba Pharmaceutical Products, Inc.
Water Solubility 239.0 mg/L 239 mg/L YALKOWSKY,SH & DANNENFELSER,RM 1992)

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.29 L/h/kg 4.83 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 2.2 L/kg 2.16 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 4.6 h 4.6 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1